8 Nov 2024 • A study on 1684 Southeast Asian patients with type 2 diabetes found that acute kidney injury (AKI) increased the risk of adverse cardio-renal outcomes and all-cause mortality.

Among participants, 219 experienced at least one AKI episode. AKI was associated with a 1.6-fold increased risk of end-stage kidney disease (ESKD), a 1.81-fold higher risk of major adverse cardiovascular events (MACE), and a 3.01-fold increased risk of all-cause death.

Even mild AKI, defined by a 0.3 mg/dL increase in serum creatinine, independently predicted a significantly higher risk of premature death.

Key predictors of AKI included age, ethnicity, cardiovascular disease history, HbA1c, baseline eGFR, and albuminuria.

The study underscores the importance of intensive surveillance and early intervention for diabetic patients who experience any episode of AKI to mitigate long-term risks of kidney and cardiovascular complications.

Source: Scientific Reports Read full story