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Sudden Cardiac Arrest in Type 2 Diabetes: Uncovering Key Risk Factors

19 Nov 2024 • A recent study examining sudden cardiac arrest (SCA) in people with Type 2 Diabetes (T2D) reveal significant associations with clinical factors and medications.

The study found that low fasting glucose, heart failure, and the use of certain medications, including antihypertensives, glucose-lowering drugs, and QTc-prolonging medications (such as prokinetics, antibiotics, and antipsychotics), are linked to an increased risk of SCA.

Specifically, patients using QTc-prolonging antibiotics and antipsychotics had a higher risk of SCA, particularly if they did not have pre-existing cardiovascular disease (CVD).

The study analyzed data from 689 SCA patients and 3,230 controls, collected from GPs’ electronic health records.

Multivariable models indicated that medications like insulin, oral glucose-lowering drugs, and certain heart failure treatments contributed to elevated SCA risk.

These findings highlight the importance of closely monitoring clinical factors and medication use in managing SCA risk in T2D patients, especially those without CVD. Source: Diabetes Care Read full story

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