4 Dec 2024 • Among generally healthy older adults who are not at high risk for diabetes and who have serum 25(OH)D3 levels that are sufficient for bone health, vitamin D3 supplementation did not significantly reduce the risk of developing diabetes.

• A large-scale Finnish study, the FIND trial, examined the effects of vitamin D3 supplementation on the risk of type 2 diabetes in healthy older adults.
• Over 4.2 years, 2271 participants aged 60 and above received either a placebo or 1600 IU/day or 3200 IU/day of vitamin D3.
• Despite higher serum vitamin D levels in the supplementation groups, there was no meaningful difference in diabetes events between groups.
• The analysis showed no impact on glucose, insulin levels, or BMI changes.

These findings do not suggest benefits of long-term moderate- or high-dose vitamin D3 supplementation for incidence of type 2 diabetes or glucose metabolism or body size among generally healthy older vitamin D-sufficient men and women who were not at high risk for type 2 diabetes.

Source: Diabetologia Read Full Story