Elevated fibrinogen levels strongly correlate with the severity of diabetic foot ulcers (DFUs), a study found. 

**Key Findings:**

- Of the participants, 30.11% had severe ulcers (Wagner Grade 5), and 56.99% showed critical ischemia. 
- Fibrinogen levels rose with increasing ulcer severity, reaching a peak of 720.77 mg/dL for grade 5 ulcers. 
- Higher fibrinogen levels were linked to deeper ulcers and more significant vascular impairment, such as non-palpable pedal pulses and severe peripheral arterial disease. 
- Fibrinogen levels were also associated with C-reactive protein and comorbidities like hypertension and chronic kidney disease. 

These findings suggest that fibrinogen could be a useful biomarker for predicting DFU progression and guiding treatment strategies.

Source: Cureus | [Read Full Story](https://www.cureus.com/articles/351226-the-relationship-between-plasma-fibrinogen-levels-and-the-severity-of-diabetic-foot-ulcers-in-diabetic-patients#!/)