25 Apr 2025 • A recent study found that the platelet-to-lymphocyte ratio (PLR) is an excellent, non-invasive marker for detecting advanced liver fibrosis in chronic Hepatitis C virus (HCV) infection.

With an AUROC of 0.879 and an optimal cutoff of ≤5.41, PLR showed a sensitivity of 85.71%, specificity of 86.27%, and diagnostic accuracy of 85.98%.

Compared to established markers like APRI and FIB-4, PLR significantly outperformed both, making it a cost-effective and reliable tool for early liver disease detection, particularly in resource-limited settings.

Source: Cureus | Read Full Story