The brain accounts for only 2% of total body weight yet demands nearly 20% of resting cardiac output, making it exquisitely vulnerable to hemodynamic extremes. While midlife hypertension is an established driver of cerebral small vessel disease, white matter lesions, and vascular cognitive impairment, aggressive blood pressure lowering in older, frail adults brings its own paradox—cerebral hypoperfusion, orthostatic stress, and accelerated memory decline.

The Pressure Paradox: A Story of Blood Pressure, the Brain & Memory

Clinical Director at KIMS, Thane & Interventional Cardiologist and Structural Heart Disease Specialist

Dr. Anup Taksande

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