Senior Consultant, Professor –Ganga Ram Institute of Postgraduate Medical Education and Research. Director Heart Failure Program and Research Sir Ganga Ram Hospital, New Delhi

Although direct oral anticoagulants (DOACs) have transformed stroke prevention in atrial fibrillation, treatment switches are frequently necessitated by changes in clinical status, bleeding risk, tolerability, drug interactions, cost, or adherence. This session will explore the clinical rationale, evidence, and practical considerations for switching between DOACs, offering a structured approach to optimizing anticoagulation while maintaining efficacy, minimizing bleeding risk, and addressing real-world barriers to long-term treatment.

Switching DOACs in clinical practice: balancing efficacy, safety, adherence, and real-world barriers

This interactive case-based discussion will present a challenging real-world scenario involving a patient with atrial fibrillation undergoing PCI, highlighting the complexities of balancing thrombotic protection with bleeding risk. Following the case presentation, an expert faculty panel will discuss evidence-based strategies for selecting and optimizing antithrombotic therapy, duration of combination treatment, and individualized decision-making in line with contemporary clinical practice.

Special Case: Navigating the ‘Sweet-spot’ in antithrombotic management: Optimizing anticoagulation therapy post PCI in AF

This case-based panel discussion will examine the perioperative management of anticoagulation in patients with atrial fibrillation, focusing on the clinical decisions surrounding interruption, bridging, and timely resumption of therapy. Through a real-world case presentation followed by expert deliberation, the faculty will discuss practical, evidence-based approaches to minimizing both thromboembolic and bleeding risks while navigating diverse surgical and procedural settings.

Dr. Ashwani Mehta

3

-

-

-

Upcoming Sessions