GLP-1–based therapies have transformed the management of obesity and type 2 diabetes, but achieving the initial response is only part of the journey. What happens when patients reach their treatment goals, require dose adjustments, discontinue therapy, or begin to regain weight? Long-term follow-up and maintenance are increasingly becoming central to successful metabolic care.

This session will explore the post-GLP-1 journey, focusing on how clinicians should monitor patients, sustain treatment benefits, address weight regain, and individualize ongoing therapy. The discussion will cover treatment continuation versus discontinuation, maintenance strategies, metabolic monitoring, lifestyle interventions, and practical approaches to managing patients after GLP-1 therapy. Through clinical scenarios, the session will address the key question: once the weight comes off, how do we help patients keep it off?