This high-impact conference brings together leading experts in critical care and infectious diseases to address the growing challenge of multidrug-resistant (MDR) infections in the ICU. Through a series of focused sessions, the program explores the evolving epidemiology of resistance, advances in rapid diagnostics for CRE and MBL pathogens, and the application of PK/PD principles to optimize antibiotic therapy. Anchored in real-world clinical practice, case-based discussions and expert-led insights, the program decodes the complexities of managing resistant infections at the bedside. Together, the sessions provide a comprehensive, mechanism-to-practice perspective, equipping clinicians with actionable strategies to improve outcomes in critically ill patients facing MDR infections.