So here we are with the premiere episode of Medflix Journal Club. Dr. Desai is back with this amazing show and we have some mind boggling breakthroughs of medicine published in the month of March. Share this #MustAttendSession invite with all your friends and colleagues and stay tuned for this blockbuster live only on Medflix!

Changing Practice: March Round-up!

The greater frequency of infections in diabetic patients is caused by the hyperglycemic environment that favors immune dysfunction (e.g., damage to the neutrophil function, depression of the antioxidant system, and humoral immunity), micro- and macro-angiopathies, neuropathy, decrease in the antibacterial activity of urine, gastrointestinal and urinary dysmotility, and greater number of medical interventions in these patients. In addition to the increased morbidity, infectious processes may be the first manifestation of diabetes mellitus or the precipitating factors for complications inherent to the disease, such as diabetic ketoacidosis and hypoglycemia. The major infections associated with diabetes mellitus are diabetic foot infections, repeated UTI'S, Tuberculosis, Hepatitis B & C infections, Candidiasis, invasive external otitis and Bacterial Pyelonephritis. Let's hear from Dr. Bantwal the infections typically seen in Indian Diabetes and how to manage them.

Infections Typically seen in Indian Diabetics

Aspirin is a highly successful antiplatelet drug & still retains its status as the 'front-line' antiplatelet drug; however, any effective antiplatelet dose of aspirin is associated with an increased risk of bleeding. Hence increased understanding of platelet biology has led to the development of new antiplatelet drugs that are potentially more effective. Aspirin and P2Y12 inhibitors (clopidogrel, prasugrel and ticagrelor) are the most commonly used antiplatelet drugs, either alone or as dual antiplatelet therapy. In this discussion with leading cardiologist Dr. Jagdish Hiremath, we go over a detailed review of newer antiplatelets over aspirin and discuss the overall safety and efficacy.

Aspirin vs. Newer Antiplatelets: What Should You Choose?

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract and includes both Crohn's disease and ulcerative colitis. Given that the presentation of IBD is not specific, the differential diagnosis is broad and encompasses a wide spectrum of diseases, many of which can mimic and/or even coexist with IBD. Mycobacterium tuberculosis ('the great mimic') may coexist with IBD or mimic CD entirely. Accurate diagnosis of IBD and exclusion of these mimics are crucial for patient management. Renowned senior gastroenterologist Dr. Manish Bhatnagar helps us address these dilemmas in diagnosis with a few interesting cases and clinical scenarios! 

Diagnostic Dilemmas : IBD

Peripheral neuropathy (PN) encompasses a broad range of clinical pathologies potentially presenting with peripheral nervous system dysfunction. Patients with PN often present with varying degrees of numbness, tingling, and/or burning in the extremities. Although there are many possible causes of peripheral neuropathy, the most prevalent subtype, diabetic peripheral neuropathy, can lead to significant complications. Renowned Neurologist Dr. Rahul Kulkarni joins us on Medflix to discuss the diagnostic techniques that might aid in early detection and shed light on the recent advances in precision medicine techniques for the treatment of painful neuropathies. 

Numbness, Tingling, and Burning: Understanding Peripheral Neuropathy

Patients should be monitored closely for signs of treatment failure despite ATT. Monitoring response to treatment is done through regular history taking, physical examination, chest radiograph and laboratory monitoring. Any patient not clinically responding to therapy after several weeks should be considered at risk for failure. Let's understand what went wrong in our treatment protocol when there is no response to standard treatment regimen. 

No response to standard treatment regimen - What went wrong?

Get ready for the ultimate showdown in endocrinology! Join us for "The Endocrine Quiz", hosted by Dr. Om Lakhani, Consultant Endocrinologist at Zydus Hospital. Test your knowledge and compete against your peers for a chance to win exciting prizes. This thrilling event takes place only the Medflix app. Don't miss out on this exciting opportunity to showcase your endocrine expertise!

The Endocrine Quiz

Over the past few weeks, flu cases have risen in India which is in the clutches of an influenza outbreak. H3N2 has been the dominant subtype followed by H1N1, both subtypes of Influenza 'A' . Meanwhile, Adenovirus infections is causing major concerns in the pediatric age group including deaths in certain states. RSV is creating havoc in geriatric age group. Join us live with Medflix blockbuster faculty Dr. Tushar Shah in conversation with Dr. Tanu Singhal. 

Unmasking the Current H3N2 & Other Respiratory Viral Infections

Pediatric acute liver failure is a rare, complex, rapidly progressing, and life-threatening illness. Majority of pediatric acute liver failures have unknown etiology. Pediatric acute liver failure (PALF) can be defined as: 1)Biochemical evidence of acute liver injury in a child with no known evidence of chronic liver disease along with at least one of the following, 2)INR > 1.5, not corrected with vitamin K supplementation, with encephalopathy & INR > 2.0, not corrected with vitamin K supplementation, without encephalopathy. The diagnostic evaluation for PALF should be tailored according to age of presentation. Management of PALF is challenging due to multi-organ system involvement necessitating multidisciplinary approach and potential for rapid deterioration. Medflix brings you an extremely detailed guide to the management of PALF with Dr. Maninder Singh Dhaliwal.

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