4 Dec 2023 • In a study spanning two decades and involving 476,347 participants, researchers revealed that resting heart rate may serve as a risk factor for kidney disease in individuals without established cardiovascular disease risk factors.

• Participants with an RHR of ≥80 bpm had a higher stage of chronic kidney disease, lower estimated glomerular filtration rate, and more proteinuria than those with an RHR of 60 to 69 bpm.
• The risk of ESRD remained significantly elevated (HR, 1.32 per 10‐beat increase from 60 bpm) after excluding participants who smoked; had hypertension, diabetes, or hyperlipidemia; or were overweight.

An RHR of ≥80 bpm is significantly associated with an increased risk of ESRD. These results suggest that RHR may serve as a risk factor for kidney disease in individuals without established cardiovascular disease risk factors.

Source: JAHA | Read full story