Extended anaerobic coverage is likely unnecessary in aspiration pneumonia because it is associated with no additional mortality benefit, only an increased risk of C. difficile colitis - as per findings published in the journal CHEST.

- Categorizing patients with aspiration pneumonia into limited anaerobic antibiotic coverage (LAC) and extended anaerobic antibiotic coverage (EAC) groups, a study found no significant difference in in-hospital mortality rates between the two groups but noted an increased risk of C. difficile colitis with EAC. 
- EAC offered no additional mortality benefit and a 1.0% elevated risk of C. difficile colitis compared to LAC. 

Source: CHEST | [Read full story](https://journal.chestnet.org/article/S0012-3692(24)00260-5/fulltext?rss=yes)