29 Mar 2024 • Despite the concern for higher ischemic risk among older adults, clinicians can safely consider abbreviating the duration of DAPT after PCI to reduce the risk of bleeding without increasing the risk of MACEs.

• As per recent research, which represents the first network meta-analysis of this shortened treatment for older adults, abbreviated DAPT (1, 3, 6, and 12 months) durations reduced bleeding risk without increasing major adverse cardiovascular events (MACE) or net adverse clinical events (NACE).

• No differences were observed in the risks of NACE or MACE for 1, 3, 6, and 12 months of DAPT However, 3 months of DAPT was associated with a lower risk of bleeding compared with 6 and 12 months of DAPT among older adults.

Source: JAMA | Read full story