CDC Issues New Guidelines on Doxycycline PEP for Bacterial STIs

5 Jun 2024 • According to the latest guidelines issued by the CDC, men who have sex with men (MSM) and transgender women (TGW) who have been diagnosed with bacterial STIs like syphilis, chlamydia, or gonorrhea in the past 12 months should receive counseling on the benefits of Doxycycline postexposure prophylaxis (PEP) in preventing bacterial STIs.

  • Upon shared decision-making, the healthcare provider should prescribe them Doxycycline (200 mg - maximum dose not to be exceeded in 24 hours) for self-administration within 72 hours of penetrative/non-penetrative sexual encounter.
  • STI testing at anatomic sites of exposure at baseline to be done and repeated every 3–6 months thereafter.
  • Every 3–6 months the need for Doxycycline PEP must be assessed.
  • A holistic approach to reducing HIV risk is needed. Counseling, STI screening, HIV PrEP, and vaccinations are to be recommended.

Source: CDC | Read full story

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