Study Shows Childhood Asthma Persists in Majority of Adults: A 60-Year Perspective
1 Jul 2024 • A 60-year follow-up study of adults with severe childhood asthma found that 90% of participants still had current asthma. Those with persistent asthma had lower lung function and higher levels of type 2 inflammatory biomarkers compared to those with asthma remission. Common comorbidities included allergic rhinitis, hypertension, eczema, and cataract.
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The study included Danish adults who had stayed at an asthma care facility in Norway during their childhood. Recruitment was done through social media and personal invitation letters. Participants completed questionnaires, underwent various tests, and were classified based on their asthma symptoms and medication use.
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Participants with persistent asthma compared to those in remission had higher total immunoglobulin E levels (p=0.03), lower FEV1% predicted (p=0.03), lower FEV1/FVC ratio (p<0.001), and numerically higher fractional exhaled nitric oxide and blood eosinophil count.
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