Shortened Oral Antibiotic Course Proves Noninferior in Treating Febrile UTIs in Children
27 Dec 2023 • Five days of oral antibiotic treatment for febrile urinary tract infections (UTIs) in kids was noninferior to the standard 10-day course.
- In the randomized controlled STOP trial, researchers investigated the efficacy of a 5-day versus a conventional 10-day course of oral amoxicillin-clavulanate for treating febrile urinary tract infections (fUTIs) in children aged 3 months to 5 years.
- Results revealed that the abbreviated regimen demonstrated noninferiority with a recurrence rate of 2.8%, compared to 14.3% in the standard group within 30 days post-treatment.
The study marks a significant stride, indicating that a 5-day course is as effective as the longer duration, potentially revolutionizing the approach to managing fUTIs in children.
Source: Pediatrics | Read full story