Tirzepatide Reduces 24-Hour Ambulatory Blood Pressure in Obese Adults

5 Feb 2024 • Tirzepatide significantly lowered the systolic blood pressure for nearly 500 adults with obesity who took the medication for about eight months, according to new research published today in Hypertension, an American Heart Association journal.

  • The current research was a planned sub-study including 600 of the participants from the SURMOUNT-1 weight loss study to determine if there was an effect on blood pressure.
  • The sub-study was designed to assess the effects of tirzepatide on blood pressure levels as measured by 24-hour ambulatory blood pressure monitoring in people with obesity but without Type 2 diabetes.
  • The blood-pressure lowering effects of tirzepatide were evident in blood pressure measures taken during both the day and night.
  • The reductions in systolic blood pressure were consistent across subgroups of participants in the study who were categorized by additional factors, including age, sex, body mass index and hypertension-related risk factors.

Source: Hypertension | Read full story

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