Time-Restricted Eating: An Effective Alternative to Calorie Restriction for Lowering Body Weight and HbA1c Levels in T2D

31 Oct 2023 • Time-restricted eating (TRE) involves confining daily food intake to 6 to 10 hours and fasting for the remaining hours. Evidence shows that limiting the eating window to 6 to 10 hours within a 24-hour period naturally reduces energy intake by 200 to 500 kcal/d. Therefore, TRE may be an attractive alternative to calorie restriction for weight loss in patients with T2D.

In a 6-month randomized clinical trial involving 75 adults with T2D, participants were randomized to 1 of 3 groups:

  • 8-hour TRE (eating 12 to 8 pm only, without calorie counting)
  • CR (25% energy restriction daily),
  • or control.

TRE was more effective for weight loss (−3.6%) than CR (−1.8%) compared with controls. However, changes in HbA1c levels did not differ between the TRE (−0.91%) and CR (−0.94%) groups compared with controls.

These findings published in JAMA imply that a TRE diet strategy without calorie counting was effective for weight loss and lowering of HbA1c levels compared with daily calorie counting in a sample of adults with T2D. The study findings also showed that TRE is safe in patients who are using either diet alone or medications to control their T2D. However, for people using sulfonylureas and/or insulin, adopting a TRE regimen will require medication changes and regular monitoring, particularly in the initial stages of the diet.

Source: JAMA | Read full story

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