6 Feb 2024 • Is the use of triptans associated with ischemic events to an extent that warrants current contraindication in patients with ischemic risk factors?

• For patients with a high-risk cardiovascular profile, avoiding triptan treatment may be rational due to concerns about triptan-associated ischemic events.
• In a case-crossover study including 4,29,612 individuals, triptan use was associated with a higher risk of ischemic events, but the risk for the individual user was very low. Patients with ischemic outcomes generally had a profile of high cardiovascular risk.
• Case patients had a median age of approximately 60 years.

Source: JAMA Neurology | Read full story