10 Oct 2024 • In addition to statins previously proven role in prevention, new findings suggest they may also result in a less severe presentation of myocardial infarction.

• In a recent nationwide study involving 66,896 patients, statin use was linked to a lower incidence of ST-elevation myocardial infarction (STEMI) compared to non-ST-elevation myocardial infarction (non-STEMI)
• The odds of experiencing STEMI were 19% lower in current statin users (odds ratio 0.81) and showed a dose-dependent relationship with longer statin exposure: those using statins for over ten years had a 25% lower chance of STEMI.
• Additionally, longer cumulative statin use correlated with reduced odds of STEMI.
• The 60-day mortality rate was notably higher for STEMI patients compared to non-STEMI, emphasizing the severity of STEMI.

These findings indicate that statin therapy, in addition to reducing myocardial infarction event rates, also result in a less severe presentation of myocardial infarctions.

Source: Atherosclerosis | Read full story