2 Mar 2024 • Bariatric surgery led to superior glycemic control compared with medical/lifestyle intervention (between-group difference in hemoglobin A1c of 1.4% at 7 years and 1.1% at 12 years), with less diabetes medication usage and higher rates of diabetes remission.

• Pooled data from four US trials spanning May 2007 to August 2013 revealed that, over 7 to 12 years, bariatric surgery yielded remarkable glycemic control superiority (1.4% and 1.1% lower hemoglobin A1c at 7 and 12 years, respectively), accompanied by reduced diabetes medication dependence and increased rates of diabetes remission.
• Notably, the study encompassed diverse procedures, including Roux-en-Y gastric bypass and sleeve gastrectomy.
• Despite increased rates of anemia, fractures, and gastrointestinal adverse events in the surgery group, major cardiovascular adverse events showed no significant differences.

Source: NEJM J-Watch | Read full story