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Colchicine's Limited Impact in Post-Ablation AF: Chest Pain Relief but No Recurrence Prevention

23 Dec 2023 • A 10-day course of colchicine (0.6 mg twice daily) following catheter ablation for atrial fibrillation (AF) failed to significantly reduce atrial arrhythmia recurrence at both the 2-week and 3-month marks post-ablation.

  • Colchicine did alleviate postablation chest pain consistent with pericarditis but came with an increased incidence of diarrhea.
  • Colchicine did not demonstrate a significant impact on cardioversion or repeat ablation.
  • During a median follow-up of 1.3 years, colchicine did not reduce a composite of emergency department visit or cardiovascular hospitalization.

Source: AHA Journals | Read full story

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