20 May 2024 • In a study across 21 hospitals in Japan, researchers investigated infection characteristics and the utility of inflammatory markers in diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic syndrome (HHS).

Among 771 patients, those with bacteremia had a mortality rate of 14%, significantly higher than the 3.3% in non-bacteremic cases.

Highlighting the significance of inflammatory markers, C-reactive protein (CRP) emerged as a standout, boasting an impressive diagnostic accuracy with an AUC of 0.85, overshadowing procalcitonin (PCT).

Factors such as age, consciousness levels, hypotension, and elevated CRP levels were identified as key predictors for bacteremia risk.

This study underscores CRP's potential as a pivotal tool in diagnosing bacteremia amidst hyperglycemic emergencies.

Source: Diabetes Research & Clinical Practice | Read full story