3 Jul 2024 • Lower vitamin D levels were associated with an increased prevalence of prediabetes in males. 

• To examine the relationship between vitamin D levels and prediabetes, this study involved 384 participants (214 males and 170 females), with a median age of 40.5 years. The prevalence of prediabetes was 35.2%. Vitamin D deficiency was present in 63.0%. Significant statistical interaction was found between sex and 25(OH)D status.

• The study found that there were sex-specific differences in this association. Lower vitamin D levels were associated with an increased prevalence of prediabetes in males, and this association was not observed among females. 

• Additionally, there was a higher prevalence of prediabetes in males compared to females at vitamin D levels below 35 nmol/L. Such a sex disparity was not evident at 25(OH)D levels above 35 nmol/L. 

These findings highlight the importance of considering sex differences in the relationship between vitamin D and prediabetes.

Source:Nutrition and Diabetes| Read full story