High BP and Cholesterol Levels in Early to Middle Life Tied to Lifelong Coronary Heart Disease Risk

21 Dec 2023 • Exposure to elevated LDL-C/SBP early in life (age ≤55 years) was linked to a higher risk of CHD, independent of later-life levels.

Genetically predicted SBP and LDL-C increase the risk of CHD independent of age

A consistent association was observed between exposure to higher LDL-C and SBP in early to middle life, leading to increased odds of incident CHD in individuals aged ≤55 years, ≤60 years, and ≤65 years.

These findings support the importance of lifelong risk factor control in young individuals, whose risk of CHD accumulates throughout life.

Source: PLoS One | Read full story

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