13 Jan 2024 • Achieving a home systolic blood pressure level below 125 mm Hg (vs. 135 or lower) was associated with a reduced 10-year risk for stroke.

The 2019 Japanese Society of Hypertension guidelines recommend targeting office blood pressure (BP) <130/80 mm Hg and home systolic BP (SBP) <125/75 mm Hg, while the 2017 American College of Cardiology/American Heart Association (ACC/AHA) guidelines recommend a BP target of <130/80 mm Hg for both office and home.

A recent study was performed to evaluate whether the home SBP target of <125 mm Hg is protective against future cardiovascular disease.

During a follow-up of 6 years, a significantly heightened stroke risk (aHR, 2.68) was observed in in patients with baseline home SBP ≥135 versus <125 mm Hg.

These data support the efficacy of strict home SBP control to <125 mm Hg recommended by the Japanese Society of Hypertension guidelines.

Source: NEJM Journal Watch | Read full story